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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK4
All Species:
24.24
Human Site:
S410
Identified Species:
41.03
UniProt:
Q13043
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13043
NP_006273.1
487
55630
S410
E
K
E
N
Q
I
N
S
F
G
K
S
V
P
G
Chimpanzee
Pan troglodytes
XP_001153224
503
57116
S426
E
K
E
T
Q
I
N
S
F
G
K
S
V
P
G
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
S410
E
K
E
N
Q
I
N
S
F
G
K
S
V
P
G
Dog
Lupus familis
XP_534432
487
55507
S410
E
K
E
N
Q
I
H
S
F
G
Q
S
V
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI11
487
55523
S410
E
K
E
N
Q
I
N
S
F
G
K
N
V
S
G
Rat
Rattus norvegicus
O54748
491
56103
S406
K
Q
D
F
K
N
K
S
H
E
N
C
D
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
P227
R
Q
C
L
V
K
S
P
D
Q
R
A
T
A
T
Chicken
Gallus gallus
Q5ZJK4
486
55318
S409
A
K
E
N
Q
V
N
S
F
G
K
N
V
S
G
Frog
Xenopus laevis
Q6PA14
485
55246
P410
K
E
N
Q
F
G
T
P
E
K
T
S
P
T
S
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
K406
F
D
K
Q
D
S
N
K
A
Q
E
G
F
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
G472
D
R
K
N
A
G
D
G
R
G
D
E
K
P
I
Honey Bee
Apis mellifera
XP_393691
465
52970
K401
E
P
H
N
N
I
S
K
F
Q
N
V
F
T
E
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
S423
E
S
S
Y
K
D
A
S
Y
N
M
M
N
T
E
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
K411
Q
E
E
A
K
Q
A
K
I
S
S
P
V
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.3
97.3
N.A.
97.3
78
N.A.
55.8
92.1
76.5
77
N.A.
45.4
62.4
52.3
64.9
Protein Similarity:
100
95.8
99.7
98.9
N.A.
98.5
89.6
N.A.
57.2
96.5
86.8
87.4
N.A.
58.5
77.8
68.4
79.1
P-Site Identity:
100
93.3
100
86.6
N.A.
86.6
6.6
N.A.
0
73.3
6.6
6.6
N.A.
20
26.6
13.3
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
33.3
N.A.
26.6
86.6
20
20
N.A.
46.6
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
15
0
8
0
0
8
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
8
8
0
8
8
8
0
8
0
8
0
8
0
0
% D
% Glu:
50
15
50
0
0
0
0
0
8
8
8
8
0
0
15
% E
% Phe:
8
0
0
8
8
0
0
0
50
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
15
0
8
0
50
0
8
0
0
43
% G
% His:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
43
0
0
8
0
0
0
0
0
8
% I
% Lys:
15
43
15
0
22
8
8
22
0
8
36
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
8
50
8
8
43
0
0
8
15
15
8
8
0
% N
% Pro:
0
8
0
0
0
0
0
15
0
0
0
8
8
36
8
% P
% Gln:
8
15
0
15
43
8
0
0
0
22
8
0
0
8
0
% Q
% Arg:
8
8
0
0
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
0
8
8
0
0
8
15
58
0
8
8
36
0
15
15
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
8
0
8
29
8
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
8
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _